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| Mitta, Guillaume; Vandenbulcke, Franck; Noel, Thierry; Romestand, Bernard; Beauvillain, Jean Claude; Salzet, Michel; Roch, Philippe. |
| In previous papers, we characterised 3 types of 4-kDa, cysteine-rich, cationic antimicrobial peptides: MGDs (for Mytilus galloprovincialis defensins), mytilins and myticins, which are abundant in the mussel hemocytes. In the present work, me revealed a differential distribution of the cells expressing the different genes. In addition, using confocal and electron microscopy, we confirmed that defensins and mytilins were partially located in different sub-types of circulating hemocytes although the peptides can be located in the same cell, and even in the same granule. We also demonstrated that mytilins exert their microbicidal effect within the cells through the process of phagosome-mytilin granule fusion leading to the co-location of ingested bacteria and... |
| Tipo: Text |
Palavras-chave: Innate immunity; Hemocyte; Mussel; Myticin; Mytilin; Defensin; Antimicrobial. |
| Ano: 2000 |
URL: http://archimer.ifremer.fr/doc/2000/publication-413.pdf |
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| Flassch, Jean-pierre; Barret, Jean; Mazurie, Joseph; Maes, P; Nicolas, J; Noel, Thierry; Paillard, C; Lepennec, M. |
| A national program started in 1989 to drive researches on Ruditapes philippinarum brown ring disease correlated with a vibrio called P1. The researches have concerned epidemiological surveys on spats and adults, treatment methods, diagnostic techniques, and anatomical and functional studies about the vibrio-clam relations. The transmissions of the disease appeared mainly related to contaminated manila clam seeds, with secondary horizontal propagation. The brown ring formation appeared to be caused by a periostracum deterioration. Taking into account some of these results, an adapted cultural technique including special care of seeds and decreased densities was proposed to the farmers. |
| Tipo: Text |
Palavras-chave: ANE; France; Brittany Ruditapes philippinarum Bivalvia Marine molluscs Vibriosis Research programmes Adults Spat Diseases Clam culture Rearing. |
| Ano: 1992 |
URL: http://archimer.ifremer.fr/doc/1992/acte-925.pdf |
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